As has repeatedly been stated, the underlying hypothesis, which in a number of cases has been supported by direct experimental evidence, is that each gene controls the production, function, and specificity of a particular enzyme.
That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.
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|Birth:||14th December, 1909|
|Death:||5th November, 1975|
Edward Lawrie Tatum was born in Boulder, Colorado, USA. He was an American geneticist. He shared half of the Nobel Prize in Physiology or Medicine in 1958 with George Wells Beadle for showing that genes control individual steps in metabolism. The other half of that year's award went to Joshua Lederberg. He attended college at the University of Chicago and received his PhD in biochemistry from the University of Wisconsin–Madison in 1934.
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